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SSRIs Associated With 40% Increase In Bleeding Risk When Used With Aspirin

Marilyn Folk BScN medical review

Medically reviewed by: Marilyn Folk, BScN.
Updated March 28, 2019

A recent study has found that "patients taking both aspirin and an SSRI had a 42% increased risk of a bleeding episode - gastrointestinal bleeding, hemorrhagic stroke or other bleeding that required hospital admission - compared with those taking aspirin alone."

"Study lead Dr Elham Rahme, assistant professor at McGill University, Montreal, Canada said: 'Clinicians must weigh the benefits of SSRI therapy against the risk of bleeding in patients with major depression following acute myocardial infarction.'"

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