Mind Body Interventions (MBIs), Such As Deep Relaxation, Reverse Changes In DNA That Cause Stress
Anxietycentre.com has been a proponent of regular deep relaxation because of the many benefits it has on reducing anxiety and reversing hyperstimulation. Regular deep relaxation was an integral part of my (Jim Folk) own recovery back in the 1980s. At that time, not much was known about why regular deep relaxation was so beneficial to recovery from anxiety disorder, but enough was known to suggest it could help. It was certainly helpful to my own recovery.
Research over the last fifteen years has made significant inroads as to the reasons why regular deep relaxation is so beneficial, especially how it can help reverse the effects of stress. For example, research over the last 10 years has found that people who regularly meditated had more control over their emotions, experienced a “quieting” and “stabilization” of the mechanisms that cause stress, and had experienced increases in brain structure in key areas of the brain. Now, the latest research has found regular meditation can change our DNA for the better. You can read the press release below:
Mind-body interventions (MBIs) such as meditation, yoga and Tai Chi don't simply relax us; they can 'reverse' the molecular reactions in our DNA which cause ill-health and depression, according to a study by the universities of Coventry and Radboud.
The research, published in the journal Frontiers in Immunology, reviews over a decade of studies analysing how the behaviour of our genes is affected by different MBIs including mindfulness and yoga.
Experts from the universities conclude that, when examined together, the 18 studies -- featuring 846 participants over 11 years -- reveal a pattern in the molecular changes which happen to the body as a result of MBIs, and how those changes benefit our mental and physical health.
The researchers focus on how gene expression is affected; in other words the way that genes activate to produce proteins which influence the biological make-up of the body, the brain and the immune system.
When a person is exposed to a stressful event, their sympathetic nervous system (SNS) -- the system responsible for the 'fight-or-flight' response -- is triggered, in turn increasing production of a molecule called nuclear factor kappa B (NF-kB) which regulates how our genes are expressed.
NF-kB translates stress by activating genes to produce proteins called cytokines that cause inflammation at cellular level -- a reaction that is useful as a short-lived fight-or-flight reaction, but if persistent leads to a higher risk of cancer, accelerated aging and psychiatric disorders like depression.
According to the study, however, people who practise MBIs exhibit the opposite effect -- namely a decrease in production of NF-kB and cytokines, leading to a reversal of the pro-inflammatory gene expression pattern and a reduction in the risk of inflammation-related diseases and conditions.
The study's authors say the inflammatory effect of the fight-or-flight response -- which also serves to temporarily bolster the immune system -- would have played an important role in humankind's hunter-gatherer prehistory, when there was a higher risk of infection from wounds.
In today's society, however, where stress is increasingly psychological and often longer-term, pro-inflammatory gene expression can be persistent and therefore more likely to cause psychiatric and medical problems. Lead investigator Ivana Buric from the Brain, Belief and Behaviour Lab in Coventry University's Centre for Psychology, Behaviour and Achievement said:
"Millions of people around the world already enjoy the health benefits of mind-body interventions like yoga or meditation, but what they perhaps don't realise is that these benefits begin at a molecular level and can change the way our genetic code goes about its business.
"These activities are leaving what we call a molecular signature in our cells, which reverses the effect that stress or anxiety would have on the body by changing how our genes are expressed. Put simply, MBIs cause the brain to steer our DNA processes along a path which improves our wellbeing.
"More needs to be done to understand these effects in greater depth, for example how they compare with other healthy interventions like exercise or nutrition. But this is an important foundation to build on to help future researchers explore the benefits of increasingly popular mind-body activities."
Materials provided by Coventry University. Note: Content may be edited for style and length.
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Authors: Jim Folk, Marilyn Folk, BScN. Last updated September 10, 2017.